Detalhe da pesquisa
1.
Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax.
Mol Cell
; 77(4): 901-912.e9, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32001105
2.
Shedding light on apoptosis at subcellular membranes.
Cell
; 151(6): 1179-84, 2012 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23217705
3.
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells.
Cell
; 149(6): 1284-97, 2012 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22632761
4.
Activity of venetoclax in patients with relapsed or refractory chronic lymphocytic leukaemia: analysis of the VENICE-1 multicentre, open-label, single-arm, phase 3b trial.
Lancet Oncol
; 25(4): 463-473, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38467131
5.
Red cell transfusion thresholds in outpatients with myelodysplastic syndromes: Results of a pilot randomized trial RBC-ENHANCE.
Transfusion
; 64(2): 223-235, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38323704
6.
Long-term follow-up of VIALE-A: Venetoclax and azacitidine in chemotherapy-ineligible untreated acute myeloid leukemia.
Am J Hematol
; 99(4): 615-624, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38343151
7.
Evaluating the economic burden of acute myeloid leukemia in Canada.
Acta Haematol
; 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38382483
8.
Final report of TKI discontinuation trial with dasatinib for the second attempt of treatment-free remission after failing the first attempt with imatinib: Treatment-free Remission Accomplished by Dasatinib (TRAD) study.
Br J Haematol
; 203(5): 781-791, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37697469
9.
Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia.
N Engl J Med
; 383(7): 617-629, 2020 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32786187
10.
High transferrin saturation predicts inferior clinical outcomes in patients with myelodysplastic syndromes.
Haematologica
; 108(2): 532-542, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35979720
11.
Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax.
Cell
; 135(6): 1074-84, 2008 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19062087
12.
BCR-ABL1 transcript doubling time as a predictor for treatment-free remission failure after imatinib discontinuation in chronic myeloid leukaemia in chronic phase.
Br J Haematol
; 196(1): 136-145, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34496035
13.
The impact of oral hypoglycemics and statins on outcomes in myelodysplastic syndromes.
Ann Hematol
; 101(5): 1023-1030, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35190844
14.
Optimal duration of imatinib treatment/deep molecular response for treatment-free remission after imatinib discontinuation from a Canadian tyrosine kinase inhibitor discontinuation trial.
Br J Haematol
; 193(4): 779-791, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33876423
15.
Patient-reported fatigue refines prognosis in higher-risk myelodysplastic syndromes (MDS): a MDS-CAN study.
Br J Haematol
; 194(2): 319-324, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34060069
16.
Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial.
Ann Hematol
; 100(5): 1181-1194, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33740113
17.
Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance.
EMBO Rep
; 19(9)2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29987135
18.
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.
Nature
; 511(7507): 90-3, 2014 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24870236
19.
Hand Mirror Cells and Hypercalcemia: A Rare Presentation of Pediatric Acute Lymphoblastic Leukemia.
J Pediatr Hematol Oncol
; 42(3): e181-e184, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30475304
20.
Differences in the mechanisms of proapoptotic BH3 proteins binding to Bcl-XL and Bcl-2 quantified in live MCF-7 cells.
Mol Cell
; 45(6): 754-63, 2012 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22464442